Molecular Genetics of Pediatric Orthopaedic Disorders by Carol A. Wise & Jonathan J. Rios
Author:Carol A. Wise & Jonathan J. Rios
Language: eng
Format: epub
Publisher: Springer New York, New York, NY
Locus
Region
Marker
Mapping method
LOD score
P value (odds ratio)
Candidate gene
Reference
IS1
19p13.3
D19S216
Genome-wide linkage in seven families
3.63
–
–
[45]
IS2
17p11.2
D17S799
Genome-wide linkage in extended family
3.20
–
–
[46]
IS3
8q12.1
D8S1136
rs1038351
Targeted linkage
association across CHD7
2.77
0.0002 (GRR=3.1)
CHD7
[48]
IS4
9q31.2-34.2
D9S2157
D9S915
Genome-wide linkage in extended family
genome-wide linkage in affected sibling pair familiesa
3.64
–
0.0005
–
–
[47, 49]
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